BECN1 modulates hematopoietic stem cells by targeting Caspase-3-GSDME-mediated pyroptosis

Hematopoietic stem cells (HSCs) maintain the blood system throughout the lifespan. However, the molecular mechanism maintaining HSC character remains not fully understood. In this study, we observed that the targeted deletion of Becn1 disrupts the blood system and impairs the reconstitution capacity...

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Detalles Bibliográficos
Autores principales: Yang, Xiuxiu, Ge, Liang, Wang, Jianwei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer Health 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8975106/
https://www.ncbi.nlm.nih.gov/pubmed/35402821
http://dx.doi.org/10.1097/BS9.0000000000000051

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8975106/
https://www.ncbi.nlm.nih.gov/pubmed/35402821
http://dx.doi.org/10.1097/BS9.0000000000000051

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