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Nuclear microRNA-466c regulates Vegfa expression in response to hypoxia

MicroRNAs are well characterized in their role in silencing gene expression by targeting 3´-UTR of mRNAs in cytoplasm. However, recent studies have shown that miRNAs have a role in the regulation of genes in the nucleus, where they are abundantly located. We show here that in mouse endothelial cell...

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Detalles Bibliográficos
Autores principales: Laitinen, Pia, Väänänen, Mari-Anna, Kolari, Ida-Liisa, Mäkinen, Petri I., Kaikkonen, Minna U., Weinberg, Marc S., Morris, Kevin V., Korhonen, Paula, Malm, Tarja, Ylä-Herttuala, Seppo, Roberts, Thomas C., Turunen, Mikko P., Turunen, Tiia A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8975276/
https://www.ncbi.nlm.nih.gov/pubmed/35358280
http://dx.doi.org/10.1371/journal.pone.0265948