Cargando…

Distribution and Structure Analysis of Fibril-Forming Peptides Focusing on Concentration Dependency

[Image: see text] We focus on the concentration dependency of fibril-forming peptides, which have the potential of aggregation by themselves. In this study, we performed replica-exchange molecular dynamics simulations of Lys-Phe-Phe-Glu (KFFE) fragments, which are known to form fibrils in experiment...

Descripción completa

Detalles Bibliográficos
Autores principales: Sakae, Yoshitake, Kawasaki, Takeshi, Okamoto, Yuko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8975544/
https://www.ncbi.nlm.nih.gov/pubmed/35382341
http://dx.doi.org/10.1021/acsomega.1c04960