An Unusual Case of Myelodysplastic Syndrome With Intrahepatic Extramedullary Hematopoiesis Leading to Liver Failure

We present a rare case of a 61-year-old male who arrived at the hospital with fatigue and was found to have pancytopenia. Following further workup, he was diagnosed with myelodysplastic syndrome. His initial bilirubin of 3.1 mg/dL rose to 38.0 mg/dL. After a liver biopsy was obtained, intrahepatic e...

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Detalles Bibliográficos
Autores principales: Ternes, Logan, Giangiacomo, Faye, Nassif, Imad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2022
Materias:
Internal Medicine
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8975614/
https://www.ncbi.nlm.nih.gov/pubmed/35382211
http://dx.doi.org/10.7759/cureus.22733
Descripción
Sumario:We present a rare case of a 61-year-old male who arrived at the hospital with fatigue and was found to have pancytopenia. Following further workup, he was diagnosed with myelodysplastic syndrome. His initial bilirubin of 3.1 mg/dL rose to 38.0 mg/dL. After a liver biopsy was obtained, intrahepatic extramedullary hematopoiesis (EMH) was diagnosed and showed the liver to be infiltrated by EMH without malignancy. Within 16 days of his stay, he developed liver failure and passed away. Although intrahepatic EMH is uncommon, EMH resulting in infiltration, liver failure, and then death is exceedingly rare.

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