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TSPAN6 is a suppressor of Ras-driven cancer

Oncogenic mutations in the small GTPase RAS contribute to ~30% of human cancers. In a Drosophila genetic screen, we identified novel and evolutionary conserved cancer genes that affect Ras-driven tumorigenesis and metastasis in Drosophila including confirmation of the tetraspanin Tsp29Fb. However, i...

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Detalles Bibliográficos
Autores principales:	Humbert, Patrick O., Pryjda, Tamara Zoranovic, Pranjic, Blanka, Farrell, Andrew, Fujikura, Kohei, de Matos Simoes, Ricardo, Karim, Rezaul, Kozieradzki, Ivona, Cronin, Shane J. F., Neely, G. Gregory, Meyer, Thomas F., Hagelkruys, Astrid, Richardson, Helena E., Penninger, Josef M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8975741/ https://www.ncbi.nlm.nih.gov/pubmed/35184157 http://dx.doi.org/10.1038/s41388-022-02223-y

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