Cargando…

Subretinal fibrosis in neovascular age-related macular degeneration: current concepts, therapeutic avenues, and future perspectives

Age-related macular degeneration (AMD) is a progressive, degenerative disease of the human retina which in its most aggressive form is associated with the formation of macular neovascularization (MNV) and subretinal fibrosis leading to irreversible blindness. MNVs contain blood vessels as well as in...

Descripción completa

Detalles Bibliográficos
Autores principales:	Tenbrock, Louis, Wolf, Julian, Boneva, Stefaniya, Schlecht, Anja, Agostini, Hansjürgen, Wieghofer, Peter, Schlunck, Günther, Lange, Clemens
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer Berlin Heidelberg 2021
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8975778/ https://www.ncbi.nlm.nih.gov/pubmed/34477966 http://dx.doi.org/10.1007/s00441-021-03514-8

Ejemplares similares

Immunosenescence in Choroidal Neovascularization (CNV)—Transcriptional Profiling of Naïve and CNV-Associated Retinal Myeloid Cells during Aging
por: Schlecht, Anja, et al.
Publicado: (2021)

Deciphering the Molecular Signature of Human Hyalocytes in Relation to Other Innate Immune Cell Populations
por: Wolf, Julian, et al.
Publicado: (2022)

In-Depth Molecular Profiling Specifies Human Retinal Microglia Identity
por: Wolf, Julian, et al.
Publicado: (2022)

Transcriptional and Distributional Profiling of Microglia in Retinal Angiomatous Proliferation
por: Schlecht, Anja, et al.
Publicado: (2022)

Secreted Phosphoprotein 1 Expression in Retinal Mononuclear Phagocytes Links Murine to Human Choroidal Neovascularization
por: Schlecht, Anja, et al.
Publicado: (2021)

Welche Bedeutung hat die Bindehaut als möglicher Übertragungsweg für eine SARS-CoV-2-Infektion?
por: Lange, Clemens, et al.
Publicado: (2020)

What is the significance of the conjunctiva as a potential transmission route for SARS-CoV-2 infections?
por: Lange, Clemens, et al.
Publicado: (2020)

3′ MACE RNA-sequencing allows for transcriptome profiling in human tissue samples after long-term storage
por: Boneva, Stefaniya, et al.
Publicado: (2020)

Transcriptional characterization of conjunctival melanoma identifies the cellular tumor microenvironment and prognostic gene signatures
por: Wolf, Julian, et al.
Publicado: (2020)

Expression of the COVID‐19 receptor ACE2 in the human conjunctiva
por: Lange, Clemens, et al.
Publicado: (2020)

Characterization of the Cellular Microenvironment and Novel Specific Biomarkers in Pterygia Using RNA Sequencing
por: Wolf, Julian, et al.
Publicado: (2022)

The role of interferon regulatory factor 8 for retinal tissue homeostasis and development of choroidal neovascularisation
por: Zhang, Peipei, et al.
Publicado: (2021)

Imaging mass cytometry for high-dimensional tissue profiling in the eye
por: Schlecht, Anja, et al.
Publicado: (2021)

Transcriptional Profiling Uncovers Human Hyalocytes as a Unique Innate Immune Cell Population
por: Boneva, Stefaniya Konstantinova, et al.
Publicado: (2020)

In-Depth Molecular Characterization of Neovascular Membranes Suggests a Role for Hyalocyte-to-Myofibroblast Transdifferentiation in Proliferative Diabetic Retinopathy
por: Boneva, Stefaniya Konstantinova, et al.
Publicado: (2021)

Sema3f Protects Against Subretinal Neovascularization In Vivo
por: Sun, Ye, et al.
Publicado: (2017)

Single-Cell Protein and Transcriptional Characterization of Epiretinal Membranes From Patients With Proliferative Vitreoretinopathy
por: Laich, Yannik, et al.
Publicado: (2022)

Baseline predictors for subretinal fibrosis in neovascular age-related macular degeneration
por: Roberts, Philipp K., et al.
Publicado: (2022)

MACE RNA sequencing analysis of conjunctival squamous cell carcinoma and papilloma using formalin-fixed paraffin-embedded tumor tissue
por: Boneva, Stefaniya, et al.
Publicado: (2020)

Webbasierte Genexpressionsanalysen – auf dem Weg zur molekularen Entschlüsselung gesunder und erkrankter Augengewebe
por: Wolf, Julian, et al.
Publicado: (2022)

Web-based gene expression analysis—paving the way to decode healthy and diseased ocular tissue
por: Wolf, Julian, et al.
Publicado: (2022)

The Effect of Topical Bromfenac on Intraretinal and Subretinal Fluid in Neovascular Age-Related Macular Degeneration
por: Abdolrahimzadeh, Solmaz, et al.
Publicado: (2020)

Subretinal Neovascular Membrane in Wet Age-Related Macular Degeneration Managed With Intravitreal Ranibizumab
por: Sharma, Tanishq S, et al.
Publicado: (2021)

Tolerating subretinal fluid in the treatment of neovascular age-related macular degeneration with intravitreal aflibercept
por: Yildiz, Dilan, et al.
Publicado: (2021)

Macrophage to myofibroblast transition contributes to subretinal fibrosis secondary to neovascular age-related macular degeneration
por: Little, Karis, et al.
Publicado: (2020)

CNTF Prevents Development of Outer Retinal Neovascularization Through Upregulation of CxCl10
por: Bucher, Felicitas, et al.
Publicado: (2020)

Three-Year Outcomes of Neovascular Age-Related Macular Degeneration in Eyes That Do Not Develop Macular Atrophy or Subretinal Fibrosis
por: Gabrielle, Pierre-Henry, et al.
Publicado: (2021)

Morphologic and Microvascular Differences Between Macular Neovascularization With and Without Subretinal Fibrosis
por: Roberts, Philipp Ken, et al.
Publicado: (2021)

Subretinal hyperreflective material morphology in neovascular age-related macular degeneration: A case control study
por: Alex, Divya, et al.
Publicado: (2021)

Erratum in: Three-Year Outcomes of Neovascular Age-Related Macular Degeneration in Eyes That Do Not Develop Macular Atrophy or Subretinal Fibrosis
Publicado: (2021)

Transient accumulation of subretinal fluid after half-fluence photodynamic therapy in neovascular age-related macular degeneration
por: Kim, Min Ho, et al.
Publicado: (2021)

Viral S protein histochemistry reveals few potential SARS-CoV-2 entry sites in human ocular tissues
por: Martin, Gottfried, et al.
Publicado: (2021)

APOE2 promotes the development and progression of subretinal neovascularization in age-related macular degeneration via MAPKs signaling pathway
por: Sun, Yiwen, et al.
Publicado: (2020)

Chorioretinal thickness and retinal pigment epithelial degeneration of fellow eyes in patients with unilateral neovascular age-related macular degeneration with subretinal drusenoid deposits
por: Kang, Dongwan, et al.
Publicado: (2022)

Longitudinal Analysis of the Choriocapillaris Using Optical Coherence Tomography Angiography Reveals Subretinal Fluid as a Substantial Confounder in Patients with Acute Central Serous Chorioretinopathy
por: Reich, Michael, et al.
Publicado: (2019)

Treatment of age-related neovascular macular degeneration: the patient’s perspective
por: Müller, S., et al.
Publicado: (2017)

Subretinal Coapplication of Tissue Plasminogen Activator and Bevacizumab with Concurrent Pneumatic Displacement for Submacular Hemorrhages Secondary to Neovascular Age-Related Macular Degeneration
por: Avcı, Remzi, et al.
Publicado: (2021)

Acquired Vitelliform Macular Degeneration: Characteristics and Challenges of Managing Subretinal Fluid
por: Juliano, Joseph, et al.
Publicado: (2021)

Histology of neovascular myopic macular degeneration
por: Jonas, Shefali B., et al.
Publicado: (2021)

Subretinal alteplase injections in massive subretinal hemorrhage due to age-related macular degeneration: A case report series
por: Ochinciuc, Radu, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_vrn5ikhj0b3n96s4d6710tfdut