Discovery of a signaling feedback circuit that defines interferon responses in myeloproliferative neoplasms

Interferons (IFNs) are key initiators and effectors of the immune response against malignant cells and also directly inhibit tumor growth. IFNα is highly effective in the treatment of myeloproliferative neoplasms (MPNs), but the mechanisms of action are unclear and it remains unknown why some patien...

Descripción completa

Detalles Bibliográficos
Autores principales: Saleiro, Diana, Wen, Jeremy Q., Kosciuczuk, Ewa M., Eckerdt, Frank, Beauchamp, Elspeth M., Oku, Chidera V., Blyth, Gavin T., Fischietti, Mariafausta, Ilut, Liliana, Colamonici, Marco, Palivos, William, Atsaves, Paula A., Tan, Dean, Kocherginsky, Masha, Weinberg, Rona Singer, Fish, Eleanor N., Crispino, John D., Hoffman, Ronald, Platanias, Leonidas C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8975834/
https://www.ncbi.nlm.nih.gov/pubmed/35365653
http://dx.doi.org/10.1038/s41467-022-29381-7

Ejemplares similares

Ejemplares similares