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Developmental pyrethroid exposure and age influence phenotypes in a Chd8 haploinsufficient autism mouse model
Hundreds of genes have been associated with autism spectrum disorder (ASD), including loss-of-function mutations in chromodomain helicase DNA binding protein 8 (Chd8). Environmental factors also are implicated in autism risk and have the potential to exacerbate phenotypes in genetically sensitized b...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8975859/ https://www.ncbi.nlm.nih.gov/pubmed/35365720 http://dx.doi.org/10.1038/s41598-022-09533-x |