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Developmental pyrethroid exposure and age influence phenotypes in a Chd8 haploinsufficient autism mouse model

Hundreds of genes have been associated with autism spectrum disorder (ASD), including loss-of-function mutations in chromodomain helicase DNA binding protein 8 (Chd8). Environmental factors also are implicated in autism risk and have the potential to exacerbate phenotypes in genetically sensitized b...

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Detalles Bibliográficos
Autores principales:	Jiménez, Jessica A., Simon, Jeremy M., Hu, Wenxin, Moy, Sheryl S., Harper, Kathryn M., Liu, Chih-Wei, Lu, Kun, Zylka, Mark J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8975859/ https://www.ncbi.nlm.nih.gov/pubmed/35365720 http://dx.doi.org/10.1038/s41598-022-09533-x

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