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Therapeutic and immunomodulatory potential of pazopanib in malignant phyllodes tumor

Malignant phyllodes tumors (PT) are rare aggressive fibroepithelial neoplasms with high metastatic potential and lack effective therapy. We established a patient-derived xenograft (PDX) and cell line model (designated MPT-S1) of malignant PT which demonstrated clinical response to pazopanib. Whole e...

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Detalles Bibliográficos
Autores principales:	Ng, Dave Yong Xiang, Li, Zhimei, Lee, Elizabeth, Kok, Jessica Sook Ting, Lee, Jing Yi, Koh, Joanna, Ng, Cedric Chuan-Young, Lim, Abner Herbert, Liu, Wei, Ng, Sheng Rong, Lim, Kah Suan, Huang, Xi Xiao, Hong, Jing Han, Guan, Peiyong, Sim, Yirong, Thike, Aye Aye, Nasir, Nur Diyana Md, Li, Shang, Tan, Puay Hoon, Teh, Bin Tean, Chan, Jason Yongsheng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8975864/ https://www.ncbi.nlm.nih.gov/pubmed/35365682 http://dx.doi.org/10.1038/s41523-022-00413-1

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