Comprehensive genomics in androgen receptor-dependent castration-resistant prostate cancer identifies an adaptation pathway mediated by opioid receptor kappa 1

Castration resistance is a lethal form of treatment failure of prostate cancer (PCa) and is associated with ligand-independent activation of the androgen receptor (AR). It is only partially understood how the AR mediates survival and castration-resistant growth of PCa upon androgen deprivation. We i...

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Detalles Bibliográficos
Autores principales: Makino, Yuki, Kamiyama, Yuki, Brown, J. B., Tanaka, Toshiya, Murakami, Ryusuke, Teramoto, Yuki, Goto, Takayuki, Akamatsu, Shusuke, Terada, Naoki, Inoue, Takahiro, Kodama, Tatsuhiko, Ogawa, Osamu, Kobayashi, Takashi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8976065/
https://www.ncbi.nlm.nih.gov/pubmed/35365763
http://dx.doi.org/10.1038/s42003-022-03227-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8976065/
https://www.ncbi.nlm.nih.gov/pubmed/35365763
http://dx.doi.org/10.1038/s42003-022-03227-w

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