Single-cell and spatial analysis reveal interaction of FAP(+) fibroblasts and SPP1(+) macrophages in colorectal cancer

Colorectal cancer (CRC) is among the most common malignancies with limited treatments other than surgery. The tumor microenvironment (TME) profiling enables the discovery of potential therapeutic targets. Here, we profile 54,103 cells from tumor and adjacent tissues to characterize cellular composit...

Descripción completa

Detalles Bibliográficos
Autores principales: Qi, Jingjing, Sun, Hongxiang, Zhang, Yao, Wang, Zhengting, Xun, Zhenzhen, Li, Ziyi, Ding, Xinyu, Bao, Rujuan, Hong, Liwen, Jia, Wenqing, Fang, Fei, Liu, Hongzhi, Chen, Lei, Zhong, Jie, Zou, Duowu, Liu, Lianxin, Han, Leng, Ginhoux, Florent, Liu, Yingbin, Ye, Youqiong, Su, Bing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8976074/
https://www.ncbi.nlm.nih.gov/pubmed/35365629
http://dx.doi.org/10.1038/s41467-022-29366-6

Ejemplares similares

Ejemplares similares