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Blockade of PD-L1/PD-1 signaling promotes osteo-/odontogenic differentiation through Ras activation

The programmed cell death ligand 1 (PD-L1) and its receptor programmed cell death 1 (PD-1) deliver inhibitory signals to regulate immunological tolerance during immune-mediated diseases. However, the role of PD-1 signaling and its blockade effect on human dental pulp stem cells (hDPSCs) differentiat...

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Detalles Bibliográficos
Autores principales: Jeon, So Mi, Lim, Je Sun, Park, Su Hwan, Kim, Hyung Joon, Kim, Hyung-Ryong, Lee, Jong-Ho
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8976080/
https://www.ncbi.nlm.nih.gov/pubmed/35365595
http://dx.doi.org/10.1038/s41368-022-00168-2