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Inhibition of colony stimulating factor-1 receptor (CSF-1R) as a potential therapeutic strategy for neurodegenerative diseases: opportunities and challenges

Microglia are specialized dynamic immune cells in the central nervous system (CNS) that plays a crucial role in brain homeostasis and in disease states. Persistent neuroinflammation is considered a hallmark of many neurodegenerative diseases, including Alzheimer’s disease (AD), Parkinson's dise...

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Detalles Bibliográficos
Autores principales: Han, Jinming, Chitu, Violeta, Stanley, E. Richard, Wszolek, Zbigniew K., Karrenbauer, Virginija Danylaité, Harris, Robert A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8976111/
https://www.ncbi.nlm.nih.gov/pubmed/35366105
http://dx.doi.org/10.1007/s00018-022-04225-1