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Risk factors associated with skeletal-related events following discontinuation of denosumab treatment among patients with bone metastases from solid tumors: A real-world machine learning approach
BACKGROUND: Clinical practice guidelines recommend the use of bone-targeting agents for preventing skeletal-related events (SREs) among patients with bone metastases from solid tumors. The anti-RANKL monoclonal antibody denosumab is approved for the prevention of SREs in patients with bone metastase...
Autores principales: | Jacobson, Dionna, Cadieux, Benoit, Higano, Celestia S., Henry, David H., Bachmann, Basia A., Rehn, Marko, Stopeck, Alison T., Saad, Hossam |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8976128/ https://www.ncbi.nlm.nih.gov/pubmed/35378840 http://dx.doi.org/10.1016/j.jbo.2022.100423 |
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