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Long-range structural preformation in yes-associated protein precedes encounter complex formation with TEAD
Yes-associated protein (YAP) is a partly intrinsically disordered protein (IDP) that plays a major role as the downstream element of the Hippo pathway. Although the structures of the complex between TEA domain transcription factors (TEADs) and the TEAD-binding domain of YAP are already well characte...
Autores principales: | Feichtinger, Michael, Beier, Andreas, Migotti, Mario, Schmid, Matthias, Bokhovchuk, Fedir, Chène, Patrick, Konrat, Robert |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8976148/ https://www.ncbi.nlm.nih.gov/pubmed/35378854 http://dx.doi.org/10.1016/j.isci.2022.104099 |
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