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New-Onset Type 1 Diabetes in Children With SARS-CoV-2 Infection

There has been a worldwide increase in cases of diabetic ketoacidosis in both adults and children with diabetes during the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic. This can be multifactorial: delayed care due to reduced medical services, fear of approaching hospitals, o...

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Autores principales: Ambati, Shashikanth, Mihic, Maya, Rosario, David Charles, Sanchez, Javier, Bakar, Adnan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8976287/
https://www.ncbi.nlm.nih.gov/pubmed/35382205
http://dx.doi.org/10.7759/cureus.22790
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author Ambati, Shashikanth
Mihic, Maya
Rosario, David Charles
Sanchez, Javier
Bakar, Adnan
author_facet Ambati, Shashikanth
Mihic, Maya
Rosario, David Charles
Sanchez, Javier
Bakar, Adnan
author_sort Ambati, Shashikanth
collection PubMed
description There has been a worldwide increase in cases of diabetic ketoacidosis in both adults and children with diabetes during the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic. This can be multifactorial: delayed care due to reduced medical services, fear of approaching hospitals, or SARS-CoV-2 infection itself. It is well-known that infection is an important trigger for diabetic ketoacidosis in children with type 1 or type 2 diabetes mellitus, but little is known whether SARS-CoV-2 infection can trigger diabetic ketoacidosis and new-onset diabetes mellitus in a child with no previous history of diabetes mellitus. The association of SARS-CoV-2 as a trigger for new-onset diabetes requires further investigation, as the incidence of diabetes is steadily rising in the pediatric population during the pandemic. This case report explores two cases where children present in diabetic ketoacidosis with concurrent SARS-CoV-2 infection and no known history of type 1 diabetes mellitus.
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spelling pubmed-89762872022-04-04 New-Onset Type 1 Diabetes in Children With SARS-CoV-2 Infection Ambati, Shashikanth Mihic, Maya Rosario, David Charles Sanchez, Javier Bakar, Adnan Cureus Endocrinology/Diabetes/Metabolism There has been a worldwide increase in cases of diabetic ketoacidosis in both adults and children with diabetes during the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic. This can be multifactorial: delayed care due to reduced medical services, fear of approaching hospitals, or SARS-CoV-2 infection itself. It is well-known that infection is an important trigger for diabetic ketoacidosis in children with type 1 or type 2 diabetes mellitus, but little is known whether SARS-CoV-2 infection can trigger diabetic ketoacidosis and new-onset diabetes mellitus in a child with no previous history of diabetes mellitus. The association of SARS-CoV-2 as a trigger for new-onset diabetes requires further investigation, as the incidence of diabetes is steadily rising in the pediatric population during the pandemic. This case report explores two cases where children present in diabetic ketoacidosis with concurrent SARS-CoV-2 infection and no known history of type 1 diabetes mellitus. Cureus 2022-03-03 /pmc/articles/PMC8976287/ /pubmed/35382205 http://dx.doi.org/10.7759/cureus.22790 Text en Copyright © 2022, Ambati et al. https://creativecommons.org/licenses/by/3.0/This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Endocrinology/Diabetes/Metabolism
Ambati, Shashikanth
Mihic, Maya
Rosario, David Charles
Sanchez, Javier
Bakar, Adnan
New-Onset Type 1 Diabetes in Children With SARS-CoV-2 Infection
title New-Onset Type 1 Diabetes in Children With SARS-CoV-2 Infection
title_full New-Onset Type 1 Diabetes in Children With SARS-CoV-2 Infection
title_fullStr New-Onset Type 1 Diabetes in Children With SARS-CoV-2 Infection
title_full_unstemmed New-Onset Type 1 Diabetes in Children With SARS-CoV-2 Infection
title_short New-Onset Type 1 Diabetes in Children With SARS-CoV-2 Infection
title_sort new-onset type 1 diabetes in children with sars-cov-2 infection
topic Endocrinology/Diabetes/Metabolism
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8976287/
https://www.ncbi.nlm.nih.gov/pubmed/35382205
http://dx.doi.org/10.7759/cureus.22790
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