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Expression status of p53 and organic cation transporter 1 is correlated with poor response to preoperative chemotherapy in esophageal squamous cell carcinoma

BACKGROUND: Esophageal squamous cell carcinoma (ESCC) is a highly malignant neoplasm. DNA-damaging drugs, such as cisplatin (CDDP) and 5-fluorouracil (5-FU), are most frequently used in preoperative chemotherapy for ESCC. However, the response to preoperative chemotherapy varies among patients. p53,...

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Detalles Bibliográficos
Autores principales: Izutsu, Masahiro, Domoto, Takanori, Kamoshida, Shingo, Ohsaki, Hiroyuki, Matsuoka, Hiroshi, Umeki, Yusuke, Shiogama, Kazuya, Hirayama, Masaya, Suda, Koichi, Uyama, Ichiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8976339/
https://www.ncbi.nlm.nih.gov/pubmed/35365176
http://dx.doi.org/10.1186/s12957-022-02571-9

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