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Inhibition of carbonic anhydrases IX/XII by SLC-0111 boosts cisplatin effects in hampering head and neck squamous carcinoma cell growth and invasion

BACKGROUND: Hypoxic tumor microenvironment (TME) contributes to the onset of many aspects of the cancer biology associated to the resistance to conventional therapies. Hypoxia is a common characteristic and negative prognostic factor in the head and neck squamous carcinomas (HNSCC) and is correlated...

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Detalles Bibliográficos
Autores principales: Sarnella, Annachiara, Ferrara, Ylenia, Auletta, Luigi, Albanese, Sandra, Cerchia, Laura, Alterio, Vincenzo, De Simone, Giuseppina, Supuran, Claudiu T., Zannetti, Antonella
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8976345/
https://www.ncbi.nlm.nih.gov/pubmed/35365193
http://dx.doi.org/10.1186/s13046-022-02345-x

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