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Inhibition of carbonic anhydrases IX/XII by SLC-0111 boosts cisplatin effects in hampering head and neck squamous carcinoma cell growth and invasion
BACKGROUND: Hypoxic tumor microenvironment (TME) contributes to the onset of many aspects of the cancer biology associated to the resistance to conventional therapies. Hypoxia is a common characteristic and negative prognostic factor in the head and neck squamous carcinomas (HNSCC) and is correlated...
Autores principales: | Sarnella, Annachiara, Ferrara, Ylenia, Auletta, Luigi, Albanese, Sandra, Cerchia, Laura, Alterio, Vincenzo, De Simone, Giuseppina, Supuran, Claudiu T., Zannetti, Antonella |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8976345/ https://www.ncbi.nlm.nih.gov/pubmed/35365193 http://dx.doi.org/10.1186/s13046-022-02345-x |
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