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Detection of Mycobacterium tuberculosis Rifampicin Resistance Conferred by Borderline rpoB Mutations: Xpert MTB/RIF is Superior to Phenotypic Drug Susceptibility Testing

OBJECTIVE: To compare the ability of detection of borderline rifampicin resistance in Mycobacterium tuberculosis between molecular assay and phenotypic drug susceptibility tests. METHODS: Fifty-seven isolates with His445Leu, Asp435Tyr, Leu452Pro, Leu430Pro, His445Asn, Ile491Phe, and His445Ser mutati...

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Detalles Bibliográficos
Autores principales:	Xia, Hui, Song, Yuanyuan, Zheng, Yang, Wang, Shengfen, Zhao, Bing, He, Wencong, Liu, Dongxin, Ou, Xichao, Zhou, Yang, Zhao, Yanlin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove 2022
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8976515/ https://www.ncbi.nlm.nih.gov/pubmed/35378895 http://dx.doi.org/10.2147/IDR.S358301

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