Pathophysiology of Dysphagia in Eosinophilic Esophagitis: Causes, Consequences, and Management

Eosinophilic esophagitis (EoE) is a leading cause of food bolus impaction in children and adults. The mechanism of dysphagia in EoE, particularly non-obstructive dysphagia, remains incompletely understood. While fibrostenotic processes appear to be critical in the development of dysphagia, somatosen...

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Detalles Bibliográficos
Autores principales: Young, Edward, Philpott, Hamish
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2022
Materias:
Invited Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8976791/
https://www.ncbi.nlm.nih.gov/pubmed/35230577
http://dx.doi.org/10.1007/s10620-022-07419-6
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author Young, Edward
Philpott, Hamish
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Philpott, Hamish
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description Eosinophilic esophagitis (EoE) is a leading cause of food bolus impaction in children and adults. The mechanism of dysphagia in EoE, particularly non-obstructive dysphagia, remains incompletely understood. While fibrostenotic processes appear to be critical in the development of dysphagia, somatosensory dysfunction and dysmotility also contribute. This review considers potential mechanisms of dysphagia and evaluates the utility of current and future treatment strategies in this context.
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spelling pubmed-89767912022-04-07 Pathophysiology of Dysphagia in Eosinophilic Esophagitis: Causes, Consequences, and Management Young, Edward Philpott, Hamish Dig Dis Sci Invited Review Eosinophilic esophagitis (EoE) is a leading cause of food bolus impaction in children and adults. The mechanism of dysphagia in EoE, particularly non-obstructive dysphagia, remains incompletely understood. While fibrostenotic processes appear to be critical in the development of dysphagia, somatosensory dysfunction and dysmotility also contribute. This review considers potential mechanisms of dysphagia and evaluates the utility of current and future treatment strategies in this context. Springer US 2022-03-01 2022 /pmc/articles/PMC8976791/ /pubmed/35230577 http://dx.doi.org/10.1007/s10620-022-07419-6 Text en © Crown 2022 https://creativecommons.org/licenses/by-nc/4.0/Open AccessThis article is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License, which permits any non-commercial use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by-nc/4.0/ (https://creativecommons.org/licenses/by-nc/4.0/) .
spellingShingle Invited Review
Young, Edward
Philpott, Hamish
Pathophysiology of Dysphagia in Eosinophilic Esophagitis: Causes, Consequences, and Management
title Pathophysiology of Dysphagia in Eosinophilic Esophagitis: Causes, Consequences, and Management
title_full Pathophysiology of Dysphagia in Eosinophilic Esophagitis: Causes, Consequences, and Management
title_fullStr Pathophysiology of Dysphagia in Eosinophilic Esophagitis: Causes, Consequences, and Management
title_full_unstemmed Pathophysiology of Dysphagia in Eosinophilic Esophagitis: Causes, Consequences, and Management
title_short Pathophysiology of Dysphagia in Eosinophilic Esophagitis: Causes, Consequences, and Management
title_sort pathophysiology of dysphagia in eosinophilic esophagitis: causes, consequences, and management
topic Invited Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8976791/
https://www.ncbi.nlm.nih.gov/pubmed/35230577
http://dx.doi.org/10.1007/s10620-022-07419-6
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