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Locus coeruleus integrity is related to tau burden and memory loss in autosomal-dominant Alzheimer’s disease

Abnormally phosphorylated tau, an indicator of Alzheimer’s disease, accumulates in the first decades of life in the locus coeruleus (LC), the brain’s main noradrenaline supply. However, technical challenges in reliable in-vivo assessments have impeded research into the role of the LC in Alzheimer’s...

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Detalles Bibliográficos
Autores principales:	Dahl, Martin J., Mather, Mara, Werkle-Bergner, Markus, Kennedy, Briana L., Guzman, Samuel, Hurth, Kyle, Miller, Carol A., Qiao, Yuchuan, Shi, Yonggang, Chui, Helena C., Ringman, John M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8976827/ https://www.ncbi.nlm.nih.gov/pubmed/35045380 http://dx.doi.org/10.1016/j.neurobiolaging.2021.11.006

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