Ultrastructural and proteomic profiling of mitochondria-associated endoplasmic reticulum membranes reveal aging signatures in striated muscle

Aging is a major risk for developing cardiac and skeletal muscle dysfunction, yet the underlying mechanism remains elusive. Here we demonstrated that the mitochondria-associated endoplasmic reticulum membranes (MAMs) in the rat heart and skeletal muscle were disrupted during aging. Using quantitativ...

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Detalles Bibliográficos
Autores principales: Lu, Xue, Gong, Yingchao, Hu, Wanyu, Mao, Yankai, Wang, Ting, Sun, Zeyu, Su, Xiaoling, Fu, Guosheng, Wang, Yanpeng, Lai, Dongwu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8976840/
https://www.ncbi.nlm.nih.gov/pubmed/35368021
http://dx.doi.org/10.1038/s41419-022-04746-4

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