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Anti-nociceptive effects of dual neuropeptide antagonist therapy in mouse model of neuropathic and inflammatory pain

BACKGROUND: Neurokinin-1 (NK1) and calcitonin gene-related peptide (CGRP) play a vital role in pain pathogenesis, and these proteins’ antagonists have attracted attention as promising pharmaceutical candidates. The authors investigated the anti-nociceptive effect of co-administration of the CGRP ant...

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Detalles Bibliográficos
Autores principales: Kim, Min Su, Kim, Bo Yeon, Saghetlians, Allen, Zhang, Xiang, Okida, Takuya, Kim, So Yeon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Pain Society 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8977203/
https://www.ncbi.nlm.nih.gov/pubmed/35354680
http://dx.doi.org/10.3344/kjp.2022.35.2.173