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CDKN3 Overcomes Bladder Cancer Cisplatin Resistance via LDHA-Dependent Glycolysis Reprogramming

BACKGROUND: Aerobic glycolysis plays an important role in bladder cancer (BLCA) progression and chemoresistance. Cyclin-dependent kinase inhibitor-3 (CDKN3), a dual-specificity protein tyrosine phosphatase, has aberrant upregulation in multiple cancer types and is associated with tumorigenesis. Howe...

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Detalles Bibliográficos
Autores principales:	Li, Mengxuan, Che, Nan, Jin, Yu, Li, Jinhua, Yang, Wanshan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove 2022
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8977226/ https://www.ncbi.nlm.nih.gov/pubmed/35388272 http://dx.doi.org/10.2147/OTT.S358008

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