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Metformin Protects against Spinal Cord Injury and Cell Pyroptosis via AMPK/NLRP3 Inflammasome Pathway

Spinal cord injury (SCI) is an extreme neurological impairment with few effective drug treatments. Pyroptosis is a recently found and proven type of programmed cell death that is characterized by a reliance on inflammatory caspases and the release of a large number of proinflammatory chemicals. Pyro...

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Detalles Bibliográficos
Autores principales: Yuan, Yajiang, Fan, Xiangyi, Guo, Zhanpeng, Zhou, Zipeng, Gao, Weiran
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8977347/
https://www.ncbi.nlm.nih.gov/pubmed/35387358
http://dx.doi.org/10.1155/2022/3634908