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Omicron: the highly mutational COVID-19 variant with immune escape
In the latter-half of 2021, as people all over the world began optimistically thinking that reopening was just a heartbeat away, providence meant otherwise, and the world was once again hit by a COVID-19 variant; this time with a record number of 32 mutations across its spike proteins and significan...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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The African Field Epidemiology Network
2022
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8977367/ https://www.ncbi.nlm.nih.gov/pubmed/35432693 http://dx.doi.org/10.11604/pamj.2022.41.84.33373 |
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author | Khajotia, Rumi |
author_facet | Khajotia, Rumi |
author_sort | Khajotia, Rumi |
collection | PubMed |
description | In the latter-half of 2021, as people all over the world began optimistically thinking that reopening was just a heartbeat away, providence meant otherwise, and the world was once again hit by a COVID-19 variant; this time with a record number of 32 mutations across its spike proteins and significantly increased transmissibility, infectiousness and immune escape. The WHO subsequently named this variant the “Omicron variant,” after yet another new Greek alphabet. Subsequently, it has been observed that the reinfection (evasion of immunity derived from prior infection) risk from the Omicron variant of the SARS-CoV-2 virus is substantially higher than from the previously identified beta and delta variants. South African researchers have found preliminary results suggesting significant and ongoing increase in the risk of reinfection with the Omicron variant in patients who previously suffered from COVID-19 infection. |
format | Online Article Text |
id | pubmed-8977367 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | The African Field Epidemiology Network |
record_format | MEDLINE/PubMed |
spelling | pubmed-89773672022-04-15 Omicron: the highly mutational COVID-19 variant with immune escape Khajotia, Rumi Pan Afr Med J Commentary In the latter-half of 2021, as people all over the world began optimistically thinking that reopening was just a heartbeat away, providence meant otherwise, and the world was once again hit by a COVID-19 variant; this time with a record number of 32 mutations across its spike proteins and significantly increased transmissibility, infectiousness and immune escape. The WHO subsequently named this variant the “Omicron variant,” after yet another new Greek alphabet. Subsequently, it has been observed that the reinfection (evasion of immunity derived from prior infection) risk from the Omicron variant of the SARS-CoV-2 virus is substantially higher than from the previously identified beta and delta variants. South African researchers have found preliminary results suggesting significant and ongoing increase in the risk of reinfection with the Omicron variant in patients who previously suffered from COVID-19 infection. The African Field Epidemiology Network 2022-01-31 /pmc/articles/PMC8977367/ /pubmed/35432693 http://dx.doi.org/10.11604/pamj.2022.41.84.33373 Text en Copyright: Rumi Khajotia et al. https://creativecommons.org/licenses/by/4.0/The Pan African Medical Journal (ISSN: 1937-8688). This is an Open Access article distributed under the terms of the Creative Commons Attribution International 4.0 License (https://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Commentary Khajotia, Rumi Omicron: the highly mutational COVID-19 variant with immune escape |
title | Omicron: the highly mutational COVID-19 variant with immune escape |
title_full | Omicron: the highly mutational COVID-19 variant with immune escape |
title_fullStr | Omicron: the highly mutational COVID-19 variant with immune escape |
title_full_unstemmed | Omicron: the highly mutational COVID-19 variant with immune escape |
title_short | Omicron: the highly mutational COVID-19 variant with immune escape |
title_sort | omicron: the highly mutational covid-19 variant with immune escape |
topic | Commentary |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8977367/ https://www.ncbi.nlm.nih.gov/pubmed/35432693 http://dx.doi.org/10.11604/pamj.2022.41.84.33373 |
work_keys_str_mv | AT khajotiarumi omicronthehighlymutationalcovid19variantwithimmuneescape |