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Subjective Difficulty Scale in Liver Transplantation: A Prospective Observational Study
The predictive value of a subjective difficulty scale (DS) after surgical procedures is unknown. The objective of this study was to evaluate the prognostic value of a DS after liver transplantation (LT) and to identify predictors of difficulty. Surgeons prospectively evaluated the difficulty of 441...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8977402/ https://www.ncbi.nlm.nih.gov/pubmed/35387395 http://dx.doi.org/10.3389/ti.2022.10308 |
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author | Kitano, Yuki Pietrasz, Daniel Fernandez-Sevilla, Elena Golse, Nicolas Vibert, Eric Sa Cunha, Antonio Azoulay, Daniel Cherqui, Daniel Baba, Hideo Adam, René Allard, Marc-Antoine |
author_facet | Kitano, Yuki Pietrasz, Daniel Fernandez-Sevilla, Elena Golse, Nicolas Vibert, Eric Sa Cunha, Antonio Azoulay, Daniel Cherqui, Daniel Baba, Hideo Adam, René Allard, Marc-Antoine |
author_sort | Kitano, Yuki |
collection | PubMed |
description | The predictive value of a subjective difficulty scale (DS) after surgical procedures is unknown. The objective of this study was to evaluate the prognostic value of a DS after liver transplantation (LT) and to identify predictors of difficulty. Surgeons prospectively evaluated the difficulty of 441 consecutive liver transplantations from donation after brain death at the end of the surgery by using a DS from 0 to 10 (“the easiest to the hardest you can imagine”). DS was associated with severe morbidity. The risk of graft loss at 1 year remained unchanged from 0 to 6 but increased beyond 6. Graft survival and patient survival of group with DS 7–10 was significantly impaired compared to groups with DS: 0–3 or DS: 4–6 but were significantly impaired for the group with DS: 7–10. Independent predictors of difficult LT (DS ≥ 7) were annular segment 1, transjugular intrahepatic portosystemic shunt, retransplantation beyond 30 days, portal vein thrombosis, and ascites. Of them, ascites was a borderline non-significant covariate (p = .04). Vascular complications occurred more often after difficult LT (20.5% vs. 5.9%), whereas there was no difference in the other types of complications. DS can be used to tailor monitoring and anticipate early complications. External validation is needed. |
format | Online Article Text |
id | pubmed-8977402 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | Frontiers Media S.A. |
record_format | MEDLINE/PubMed |
spelling | pubmed-89774022022-04-05 Subjective Difficulty Scale in Liver Transplantation: A Prospective Observational Study Kitano, Yuki Pietrasz, Daniel Fernandez-Sevilla, Elena Golse, Nicolas Vibert, Eric Sa Cunha, Antonio Azoulay, Daniel Cherqui, Daniel Baba, Hideo Adam, René Allard, Marc-Antoine Transpl Int Health Archive The predictive value of a subjective difficulty scale (DS) after surgical procedures is unknown. The objective of this study was to evaluate the prognostic value of a DS after liver transplantation (LT) and to identify predictors of difficulty. Surgeons prospectively evaluated the difficulty of 441 consecutive liver transplantations from donation after brain death at the end of the surgery by using a DS from 0 to 10 (“the easiest to the hardest you can imagine”). DS was associated with severe morbidity. The risk of graft loss at 1 year remained unchanged from 0 to 6 but increased beyond 6. Graft survival and patient survival of group with DS 7–10 was significantly impaired compared to groups with DS: 0–3 or DS: 4–6 but were significantly impaired for the group with DS: 7–10. Independent predictors of difficult LT (DS ≥ 7) were annular segment 1, transjugular intrahepatic portosystemic shunt, retransplantation beyond 30 days, portal vein thrombosis, and ascites. Of them, ascites was a borderline non-significant covariate (p = .04). Vascular complications occurred more often after difficult LT (20.5% vs. 5.9%), whereas there was no difference in the other types of complications. DS can be used to tailor monitoring and anticipate early complications. External validation is needed. Frontiers Media S.A. 2022-03-21 /pmc/articles/PMC8977402/ /pubmed/35387395 http://dx.doi.org/10.3389/ti.2022.10308 Text en Copyright © 2022 Kitano, Pietrasz, Fernandez-Sevilla, Golse, Vibert, Sa Cunha, Azoulay, Cherqui, Baba, Adam and Allard. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms. |
spellingShingle | Health Archive Kitano, Yuki Pietrasz, Daniel Fernandez-Sevilla, Elena Golse, Nicolas Vibert, Eric Sa Cunha, Antonio Azoulay, Daniel Cherqui, Daniel Baba, Hideo Adam, René Allard, Marc-Antoine Subjective Difficulty Scale in Liver Transplantation: A Prospective Observational Study |
title | Subjective Difficulty Scale in Liver Transplantation: A Prospective Observational Study |
title_full | Subjective Difficulty Scale in Liver Transplantation: A Prospective Observational Study |
title_fullStr | Subjective Difficulty Scale in Liver Transplantation: A Prospective Observational Study |
title_full_unstemmed | Subjective Difficulty Scale in Liver Transplantation: A Prospective Observational Study |
title_short | Subjective Difficulty Scale in Liver Transplantation: A Prospective Observational Study |
title_sort | subjective difficulty scale in liver transplantation: a prospective observational study |
topic | Health Archive |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8977402/ https://www.ncbi.nlm.nih.gov/pubmed/35387395 http://dx.doi.org/10.3389/ti.2022.10308 |
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