Cargando…

Subjective Difficulty Scale in Liver Transplantation: A Prospective Observational Study

The predictive value of a subjective difficulty scale (DS) after surgical procedures is unknown. The objective of this study was to evaluate the prognostic value of a DS after liver transplantation (LT) and to identify predictors of difficulty. Surgeons prospectively evaluated the difficulty of 441...

Descripción completa

Detalles Bibliográficos
Autores principales: Kitano, Yuki, Pietrasz, Daniel, Fernandez-Sevilla, Elena, Golse, Nicolas, Vibert, Eric, Sa Cunha, Antonio, Azoulay, Daniel, Cherqui, Daniel, Baba, Hideo, Adam, René, Allard, Marc-Antoine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8977402/
https://www.ncbi.nlm.nih.gov/pubmed/35387395
http://dx.doi.org/10.3389/ti.2022.10308
_version_ 1784680755492814848
author Kitano, Yuki
Pietrasz, Daniel
Fernandez-Sevilla, Elena
Golse, Nicolas
Vibert, Eric
Sa Cunha, Antonio
Azoulay, Daniel
Cherqui, Daniel
Baba, Hideo
Adam, René
Allard, Marc-Antoine
author_facet Kitano, Yuki
Pietrasz, Daniel
Fernandez-Sevilla, Elena
Golse, Nicolas
Vibert, Eric
Sa Cunha, Antonio
Azoulay, Daniel
Cherqui, Daniel
Baba, Hideo
Adam, René
Allard, Marc-Antoine
author_sort Kitano, Yuki
collection PubMed
description The predictive value of a subjective difficulty scale (DS) after surgical procedures is unknown. The objective of this study was to evaluate the prognostic value of a DS after liver transplantation (LT) and to identify predictors of difficulty. Surgeons prospectively evaluated the difficulty of 441 consecutive liver transplantations from donation after brain death at the end of the surgery by using a DS from 0 to 10 (“the easiest to the hardest you can imagine”). DS was associated with severe morbidity. The risk of graft loss at 1 year remained unchanged from 0 to 6 but increased beyond 6. Graft survival and patient survival of group with DS 7–10 was significantly impaired compared to groups with DS: 0–3 or DS: 4–6 but were significantly impaired for the group with DS: 7–10. Independent predictors of difficult LT (DS ≥ 7) were annular segment 1, transjugular intrahepatic portosystemic shunt, retransplantation beyond 30 days, portal vein thrombosis, and ascites. Of them, ascites was a borderline non-significant covariate (p = .04). Vascular complications occurred more often after difficult LT (20.5% vs. 5.9%), whereas there was no difference in the other types of complications. DS can be used to tailor monitoring and anticipate early complications. External validation is needed.
format Online
Article
Text
id pubmed-8977402
institution National Center for Biotechnology Information
language English
publishDate 2022
publisher Frontiers Media S.A.
record_format MEDLINE/PubMed
spelling pubmed-89774022022-04-05 Subjective Difficulty Scale in Liver Transplantation: A Prospective Observational Study Kitano, Yuki Pietrasz, Daniel Fernandez-Sevilla, Elena Golse, Nicolas Vibert, Eric Sa Cunha, Antonio Azoulay, Daniel Cherqui, Daniel Baba, Hideo Adam, René Allard, Marc-Antoine Transpl Int Health Archive The predictive value of a subjective difficulty scale (DS) after surgical procedures is unknown. The objective of this study was to evaluate the prognostic value of a DS after liver transplantation (LT) and to identify predictors of difficulty. Surgeons prospectively evaluated the difficulty of 441 consecutive liver transplantations from donation after brain death at the end of the surgery by using a DS from 0 to 10 (“the easiest to the hardest you can imagine”). DS was associated with severe morbidity. The risk of graft loss at 1 year remained unchanged from 0 to 6 but increased beyond 6. Graft survival and patient survival of group with DS 7–10 was significantly impaired compared to groups with DS: 0–3 or DS: 4–6 but were significantly impaired for the group with DS: 7–10. Independent predictors of difficult LT (DS ≥ 7) were annular segment 1, transjugular intrahepatic portosystemic shunt, retransplantation beyond 30 days, portal vein thrombosis, and ascites. Of them, ascites was a borderline non-significant covariate (p = .04). Vascular complications occurred more often after difficult LT (20.5% vs. 5.9%), whereas there was no difference in the other types of complications. DS can be used to tailor monitoring and anticipate early complications. External validation is needed. Frontiers Media S.A. 2022-03-21 /pmc/articles/PMC8977402/ /pubmed/35387395 http://dx.doi.org/10.3389/ti.2022.10308 Text en Copyright © 2022 Kitano, Pietrasz, Fernandez-Sevilla, Golse, Vibert, Sa Cunha, Azoulay, Cherqui, Baba, Adam and Allard. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Health Archive
Kitano, Yuki
Pietrasz, Daniel
Fernandez-Sevilla, Elena
Golse, Nicolas
Vibert, Eric
Sa Cunha, Antonio
Azoulay, Daniel
Cherqui, Daniel
Baba, Hideo
Adam, René
Allard, Marc-Antoine
Subjective Difficulty Scale in Liver Transplantation: A Prospective Observational Study
title Subjective Difficulty Scale in Liver Transplantation: A Prospective Observational Study
title_full Subjective Difficulty Scale in Liver Transplantation: A Prospective Observational Study
title_fullStr Subjective Difficulty Scale in Liver Transplantation: A Prospective Observational Study
title_full_unstemmed Subjective Difficulty Scale in Liver Transplantation: A Prospective Observational Study
title_short Subjective Difficulty Scale in Liver Transplantation: A Prospective Observational Study
title_sort subjective difficulty scale in liver transplantation: a prospective observational study
topic Health Archive
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8977402/
https://www.ncbi.nlm.nih.gov/pubmed/35387395
http://dx.doi.org/10.3389/ti.2022.10308
work_keys_str_mv AT kitanoyuki subjectivedifficultyscaleinlivertransplantationaprospectiveobservationalstudy
AT pietraszdaniel subjectivedifficultyscaleinlivertransplantationaprospectiveobservationalstudy
AT fernandezsevillaelena subjectivedifficultyscaleinlivertransplantationaprospectiveobservationalstudy
AT golsenicolas subjectivedifficultyscaleinlivertransplantationaprospectiveobservationalstudy
AT viberteric subjectivedifficultyscaleinlivertransplantationaprospectiveobservationalstudy
AT sacunhaantonio subjectivedifficultyscaleinlivertransplantationaprospectiveobservationalstudy
AT azoulaydaniel subjectivedifficultyscaleinlivertransplantationaprospectiveobservationalstudy
AT cherquidaniel subjectivedifficultyscaleinlivertransplantationaprospectiveobservationalstudy
AT babahideo subjectivedifficultyscaleinlivertransplantationaprospectiveobservationalstudy
AT adamrene subjectivedifficultyscaleinlivertransplantationaprospectiveobservationalstudy
AT allardmarcantoine subjectivedifficultyscaleinlivertransplantationaprospectiveobservationalstudy