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CD8(+) T-Cell Exhaustion Phenotype in Chronic Hepatitis C Virus Infection Is Associated With Epitope Sequence Variation

BACKGROUND AND AIMS: During chronic hepatitis C virus (HCV) infection, CD8(+) T-cells become functionally exhausted, undergoing progressive phenotypic changes, i.e., overexpression of “inhibitory” molecules such as PD-1 (programmed cell death protein 1) and/or Tim-3 (T-cell immunoglobulin and mucin...

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Detalles Bibliográficos
Autores principales:	Osuch, Sylwia, Laskus, Tomasz, Perlejewski, Karol, Berak, Hanna, Bukowska-Ośko, Iwona, Pollak, Agnieszka, Zielenkiewicz, Magdalena, Radkowski, Marek, Caraballo Cortés, Kamila
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8977521/ https://www.ncbi.nlm.nih.gov/pubmed/35386708 http://dx.doi.org/10.3389/fimmu.2022.832206

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