The Role of microRNA in the Inflammatory Response of Wound Healing

Wound healing, a highly complex pathophysiological response to injury, includes four overlapping phases of hemostasis, inflammation, proliferation, and remodeling. Initiation and resolution of the inflammatory response are the primary requirements for wound healing, and are also key events that dete...

Descripción completa

Detalles Bibliográficos
Autores principales: Jiang, Yuanyuan, Xu, Xiang, Xiao, Long, Wang, Lihong, Qiang, Sheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8977525/
https://www.ncbi.nlm.nih.gov/pubmed/35386721
http://dx.doi.org/10.3389/fimmu.2022.852419
_version_ 1784680783768715264
author Jiang, Yuanyuan
Xu, Xiang
Xiao, Long
Wang, Lihong
Qiang, Sheng
author_facet Jiang, Yuanyuan
Xu, Xiang
Xiao, Long
Wang, Lihong
Qiang, Sheng
author_sort Jiang, Yuanyuan
collection PubMed
description Wound healing, a highly complex pathophysiological response to injury, includes four overlapping phases of hemostasis, inflammation, proliferation, and remodeling. Initiation and resolution of the inflammatory response are the primary requirements for wound healing, and are also key events that determines wound quality and healing time. Currently, the number of patients with persistent chronic wounds has generally increased, which imposes health and economic burden on patients and society. Recent studies have found that microRNA(miRNA) plays an essential role in the inflammation involved in wound healing and may provide a new therapeutic direction for wound treatment. Therefore, this review focused on the role and significance of miRNA in the inflammation phase of wound healing.
format Online
Article
Text
id pubmed-8977525
institution National Center for Biotechnology Information
language English
publishDate 2022
publisher Frontiers Media S.A.
record_format MEDLINE/PubMed
spelling pubmed-89775252022-04-05 The Role of microRNA in the Inflammatory Response of Wound Healing Jiang, Yuanyuan Xu, Xiang Xiao, Long Wang, Lihong Qiang, Sheng Front Immunol Immunology Wound healing, a highly complex pathophysiological response to injury, includes four overlapping phases of hemostasis, inflammation, proliferation, and remodeling. Initiation and resolution of the inflammatory response are the primary requirements for wound healing, and are also key events that determines wound quality and healing time. Currently, the number of patients with persistent chronic wounds has generally increased, which imposes health and economic burden on patients and society. Recent studies have found that microRNA(miRNA) plays an essential role in the inflammation involved in wound healing and may provide a new therapeutic direction for wound treatment. Therefore, this review focused on the role and significance of miRNA in the inflammation phase of wound healing. Frontiers Media S.A. 2022-03-21 /pmc/articles/PMC8977525/ /pubmed/35386721 http://dx.doi.org/10.3389/fimmu.2022.852419 Text en Copyright © 2022 Jiang, Xu, Xiao, Wang and Qiang https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Immunology
Jiang, Yuanyuan
Xu, Xiang
Xiao, Long
Wang, Lihong
Qiang, Sheng
The Role of microRNA in the Inflammatory Response of Wound Healing
title The Role of microRNA in the Inflammatory Response of Wound Healing
title_full The Role of microRNA in the Inflammatory Response of Wound Healing
title_fullStr The Role of microRNA in the Inflammatory Response of Wound Healing
title_full_unstemmed The Role of microRNA in the Inflammatory Response of Wound Healing
title_short The Role of microRNA in the Inflammatory Response of Wound Healing
title_sort role of microrna in the inflammatory response of wound healing
topic Immunology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8977525/
https://www.ncbi.nlm.nih.gov/pubmed/35386721
http://dx.doi.org/10.3389/fimmu.2022.852419
work_keys_str_mv AT jiangyuanyuan theroleofmicrornaintheinflammatoryresponseofwoundhealing
AT xuxiang theroleofmicrornaintheinflammatoryresponseofwoundhealing
AT xiaolong theroleofmicrornaintheinflammatoryresponseofwoundhealing
AT wanglihong theroleofmicrornaintheinflammatoryresponseofwoundhealing
AT qiangsheng theroleofmicrornaintheinflammatoryresponseofwoundhealing
AT jiangyuanyuan roleofmicrornaintheinflammatoryresponseofwoundhealing
AT xuxiang roleofmicrornaintheinflammatoryresponseofwoundhealing
AT xiaolong roleofmicrornaintheinflammatoryresponseofwoundhealing
AT wanglihong roleofmicrornaintheinflammatoryresponseofwoundhealing
AT qiangsheng roleofmicrornaintheinflammatoryresponseofwoundhealing

Ejemplares similares