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Pitavastatin Induces Cancer Cell Apoptosis by Blocking Autophagy Flux
Statins, a class of lipid-lowering drugs, are used in drug repositioning for treatment of human cancer. However, the molecular mechanisms underlying statin-induced cancer cell death and autophagy are not clearly defined. In the present study, we showed that pitavastatin could increase apoptosis in a...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Media S.A.
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8977529/ https://www.ncbi.nlm.nih.gov/pubmed/35387352 http://dx.doi.org/10.3389/fphar.2022.854506 |