A targetable ‘rogue’ neutrophil-subset, [CD11b+DEspR+] immunotype, is associated with severity and mortality in acute respiratory distress syndrome (ARDS) and COVID-19-ARDS

Neutrophil-mediated secondary tissue injury underlies acute respiratory distress syndrome (ARDS) and progression to multi-organ-failure (MOF) and death, processes linked to COVID-19-ARDS. This secondary tissue injury arises from dysregulated neutrophils and neutrophil extracellular traps (NETs) inte...

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Detalles Bibliográficos
Autores principales: Herrera, Victoria L. M., Walkey, Allan J., Nguyen, Mai Q., Gromisch, Christopher M., Mosaddhegi, Julie Z., Gromisch, Matthew S., Jundi, Bakr, Lukassen, Soeren, Carstensen, Saskia, Denis, Ridiane, Belkina, Anna C., Baron, Rebecca M., Pinilla-Vera, Mayra, Mueller, Meike, Kimberly, W. Taylor, Goldstein, Joshua N., Lehmann, Irina, Shih, Angela R., Eils, Roland, Levy, Bruce D., Ruiz-Opazo, Nelson
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8977568/
https://www.ncbi.nlm.nih.gov/pubmed/35379853
http://dx.doi.org/10.1038/s41598-022-09343-1

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