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Parallel Manipulation and Flexible Assembly of Micro-Spiral via Optoelectronic Tweezers

Micro-spiral has a wide range of applications in smart materials, such as drug delivery, deformable materials, and micro-scale electronic devices by utilizing the manipulation of electric fields, magnetic fields, and flow fields. However, it is incredibly challenging to achieve a massively parallel...

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Autores principales: Liang, Shuzhang, Sun, Jiayu, Zhang, Chaonan, Zhu, Zixi, Dai, Yuguo, Gan, Chunyuan, Cai, Jun, Chen, Huawei, Feng, Lin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8977588/
https://www.ncbi.nlm.nih.gov/pubmed/35387303
http://dx.doi.org/10.3389/fbioe.2022.868821
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author Liang, Shuzhang
Sun, Jiayu
Zhang, Chaonan
Zhu, Zixi
Dai, Yuguo
Gan, Chunyuan
Cai, Jun
Chen, Huawei
Feng, Lin
author_facet Liang, Shuzhang
Sun, Jiayu
Zhang, Chaonan
Zhu, Zixi
Dai, Yuguo
Gan, Chunyuan
Cai, Jun
Chen, Huawei
Feng, Lin
author_sort Liang, Shuzhang
collection PubMed
description Micro-spiral has a wide range of applications in smart materials, such as drug delivery, deformable materials, and micro-scale electronic devices by utilizing the manipulation of electric fields, magnetic fields, and flow fields. However, it is incredibly challenging to achieve a massively parallel manipulation of the micro-spiral to form a particular microstructure in these conventional methods. Here, a simple method is reported for assembling micro-spirals into various microstructures via optoelectronic tweezers (OETs), which can accurately manipulate the micro-/bio-particles by projecting light patterns. The manipulation force of micro-spiral is analyzed and simulated first by the finite element simulation. When the micro-spiral lies at the bottom of the microfluidic chip, it can be translated or rotated toward the target position by applying control forces simultaneously at multiple locations on the long axis of the micro-spiral. Through the OET manipulation, the length of the micro-spiral chain can reach 806.45 μm. Moreover, the different parallel manipulation modes are achieved by utilizing multiple light spots. The results show that the micro-spirulina can be manipulated by a real-time local light pattern and be flexibly assembled into design microstructures by OETs, such as a T-shape circuit, link lever, and micro-coil pairs of devices. This assembly method using OETs has promising potential in fabricating innovative materials and microdevices for practical engineering applications.
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spelling pubmed-89775882022-04-05 Parallel Manipulation and Flexible Assembly of Micro-Spiral via Optoelectronic Tweezers Liang, Shuzhang Sun, Jiayu Zhang, Chaonan Zhu, Zixi Dai, Yuguo Gan, Chunyuan Cai, Jun Chen, Huawei Feng, Lin Front Bioeng Biotechnol Bioengineering and Biotechnology Micro-spiral has a wide range of applications in smart materials, such as drug delivery, deformable materials, and micro-scale electronic devices by utilizing the manipulation of electric fields, magnetic fields, and flow fields. However, it is incredibly challenging to achieve a massively parallel manipulation of the micro-spiral to form a particular microstructure in these conventional methods. Here, a simple method is reported for assembling micro-spirals into various microstructures via optoelectronic tweezers (OETs), which can accurately manipulate the micro-/bio-particles by projecting light patterns. The manipulation force of micro-spiral is analyzed and simulated first by the finite element simulation. When the micro-spiral lies at the bottom of the microfluidic chip, it can be translated or rotated toward the target position by applying control forces simultaneously at multiple locations on the long axis of the micro-spiral. Through the OET manipulation, the length of the micro-spiral chain can reach 806.45 μm. Moreover, the different parallel manipulation modes are achieved by utilizing multiple light spots. The results show that the micro-spirulina can be manipulated by a real-time local light pattern and be flexibly assembled into design microstructures by OETs, such as a T-shape circuit, link lever, and micro-coil pairs of devices. This assembly method using OETs has promising potential in fabricating innovative materials and microdevices for practical engineering applications. Frontiers Media S.A. 2022-03-21 /pmc/articles/PMC8977588/ /pubmed/35387303 http://dx.doi.org/10.3389/fbioe.2022.868821 Text en Copyright © 2022 Liang, Sun, Zhang, Zhu, Dai, Gan, Cai, Chen and Feng. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Bioengineering and Biotechnology
Liang, Shuzhang
Sun, Jiayu
Zhang, Chaonan
Zhu, Zixi
Dai, Yuguo
Gan, Chunyuan
Cai, Jun
Chen, Huawei
Feng, Lin
Parallel Manipulation and Flexible Assembly of Micro-Spiral via Optoelectronic Tweezers
title Parallel Manipulation and Flexible Assembly of Micro-Spiral via Optoelectronic Tweezers
title_full Parallel Manipulation and Flexible Assembly of Micro-Spiral via Optoelectronic Tweezers
title_fullStr Parallel Manipulation and Flexible Assembly of Micro-Spiral via Optoelectronic Tweezers
title_full_unstemmed Parallel Manipulation and Flexible Assembly of Micro-Spiral via Optoelectronic Tweezers
title_short Parallel Manipulation and Flexible Assembly of Micro-Spiral via Optoelectronic Tweezers
title_sort parallel manipulation and flexible assembly of micro-spiral via optoelectronic tweezers
topic Bioengineering and Biotechnology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8977588/
https://www.ncbi.nlm.nih.gov/pubmed/35387303
http://dx.doi.org/10.3389/fbioe.2022.868821
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