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Trimetazidine and exercise offer analogous improvements to the skeletal muscle insulin resistance of mice through Nrf2 signaling

INTRODUCTION: Insulin resistance (IR) plays a key role in the pathogenesis and clinical course of patients with multiple metabolic diseases and diabetes. This study aimed to explore the effect of trimetazidine (TMZ) on skeletal muscle IR in mice fed a high-fat diet (HFD) and explore the possible und...

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Detalles Bibliográficos
Autores principales:	Zhang, Wenliang, Dun, Yaoshan, You, Baiyang, Qiu, Ling, Ripley-Gonzalez, Jeffrey W, Cheng, Jing, Fu, Siqian, Li, Cui, Liu, Suixin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BMJ Publishing Group 2022
Materias:	Metabolism
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8977813/ https://www.ncbi.nlm.nih.gov/pubmed/35365489 http://dx.doi.org/10.1136/bmjdrc-2021-002699

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