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PDE4B Is a Homeostatic Regulator of Cyclic AMP in Dendritic Cells

Chronic decreases in the second messenger cyclic AMP (cAMP) occur in numerous settings, but how cells compensate for such decreases is unknown. We have used a unique system—murine dendritic cells (DCs) with a DC-selective depletion of the heterotrimeric GTP binding protein Gα(s)—to address this issu...

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Detalles Bibliográficos
Autores principales:	Chinn, Amy M., Salmerón, Cristina, Lee, Jihyung, Sriram, Krishna, Raz, Eyal, Insel, Paul A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Pharmacology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8977838/ https://www.ncbi.nlm.nih.gov/pubmed/35387344 http://dx.doi.org/10.3389/fphar.2022.833832

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