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Muscle cells of sporadic amyotrophic lateral sclerosis patients secrete neurotoxic vesicles
BACKGROUND: The cause of the motor neuron (MN) death that drives terminal pathology in amyotrophic lateral sclerosis (ALS) remains unknown, and it is thought that the cellular environment of the MN may play a key role in MN survival. Several lines of evidence implicate vesicles in ALS, including tha...
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