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Cathepsin K activity controls cachexia‐induced muscle atrophy via the modulation of IRS1 ubiquitination

BACKGROUND: Cachexia is a complicated metabolic disorder that is characterize by progressive atrophy of skeletal muscle. Cathepsin K (CTSK) is a widely expressed cysteine protease that has garnered attention because of its enzymatic and non‐enzymatic functions in signalling in various pathological c...

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Detalles Bibliográficos
Autores principales:	Meng, Xiangkun, Huang, Zhe, Inoue, Aiko, Wang, Hailong, Wan, Ying, Yue, Xueling, Xu, Shengnan, Jin, Xueying, Shi, Guo‐Ping, Kuzuya, Masafumi, Cheng, Xian Wu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2022
Materias:	Original Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8978007/ https://www.ncbi.nlm.nih.gov/pubmed/35098692 http://dx.doi.org/10.1002/jcsm.12919

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