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The Emerging Roles of the β-Secretase BACE1 and the Long Non-coding RNA BACE1-AS in Human Diseases: A Focus on Neurodegenerative Diseases and Cancer

The β-Secretase (BACE1) is widely studied to be particularly involved in amyloid deposition, a process known as the pathogenic pathway in neurodegenerative diseases. Therefore, BACE1 expression is frequently reported to be upregulated in brain samples of the patients with Alzheimer’s disease (AD). B...

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Detalles Bibliográficos
Autores principales: Sayad, Arezou, Najafi, Sajad, Hussen, Bashdar Mahmud, Abdullah, Sara Tharwat, Movahedpour, Ahmad, Taheri, Mohammad, Hajiesmaeili, Mohammadreza
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8978056/
https://www.ncbi.nlm.nih.gov/pubmed/35386116
http://dx.doi.org/10.3389/fnagi.2022.853180