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Cannabidiol‐induced activation of the metallothionein pathway impedes anticancer effects of disulfiram and its metabolite CuET

Disulfiram (DSF), an established alcohol‐aversion drug, is a candidate for repurposing in cancer treatment. DSF’s antitumor activity is supported by preclinical studies, case reports, and small clinical trials; however, ongoing clinical trials of advanced‐stage cancer patients encounter variable res...

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Detalles Bibliográficos
Autores principales:	Buchtova, Tereza, Skrott, Zdenek, Chroma, Katarina, Rehulka, Jiri, Dzubak, Petr, Hajduch, Marian, Lukac, David, Arampatzis, Stefanos, Bartek, Jiri, Mistrik, Martin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2021
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8978514/ https://www.ncbi.nlm.nih.gov/pubmed/34632694 http://dx.doi.org/10.1002/1878-0261.13114

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