Cargando…
NCOA4-Mediated Ferroptosis in Bronchial Epithelial Cells Promotes Macrophage M2 Polarization in COPD Emphysema
BACKGROUND: Macrophage polarization plays an important role in the pathogenesis of COPD emphysema. Changes in macrophage polarization in COPD remain unclear, while polarization and ferroptosis are essential factors in its pathogenesis. Therefore, this study investigated the relationship between macr...
Autores principales: | Liu, Jiaxin, Zhang, Zixiao, Yang, Yue, Di, Tingting, Wu, Yan, Bian, Tao |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8978690/ https://www.ncbi.nlm.nih.gov/pubmed/35386390 http://dx.doi.org/10.2147/COPD.S354896 |
Ejemplares similares
-
Dynamic evolution of emphysema and airway remodeling in two mouse models of COPD
por: Yang, Yue, et al.
Publicado: (2021) -
MicroRNA Let-7 Induces M2 Macrophage Polarization in COPD Emphysema Through the IL-6/STAT3 Pathway
por: Liu, Tingting, et al.
Publicado: (2023) -
Hypermethylation of the Nrf2 Promoter Induces Ferroptosis by Inhibiting the Nrf2-GPX4 Axis in COPD
por: Zhang, Zixiao, et al.
Publicado: (2021) -
NCOA4-mediated ferritinophagy is involved in ionizing radiation-induced ferroptosis of intestinal epithelial cells
por: Zhou, Hao, et al.
Publicado: (2022) -
The interaction between STING and NCOA4 exacerbates lethal sepsis by orchestrating ferroptosis and inflammatory responses in macrophages
por: Wu, Jie, et al.
Publicado: (2022)