Tentative Application of a Streamlined Protocol to Determine Organ-Specific Regulations of Deiodinase 1 and Dehalogenase Activities as Readouts of the Hypothalamus-Pituitary-Thyroid-Periphery-Axis

In animal studies, both in basic science and in toxicological assessment of potential endocrine disruptors, the state of the thyroid hormone (TH) axis is often described and defined exclusively by the concentrations of circulating THs and TSH. Although it is known that the local, organ-specific effe...

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Detalles Bibliográficos
Autores principales: Renko, Kostja, Kerp, Helena, Pape, Janina, Rijntjes, Eddy, Burgdorf, Tanja, Führer, Dagmar, Köhrle, Josef
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Toxicology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8978789/
https://www.ncbi.nlm.nih.gov/pubmed/35387426
http://dx.doi.org/10.3389/ftox.2022.822993

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8978789/
https://www.ncbi.nlm.nih.gov/pubmed/35387426
http://dx.doi.org/10.3389/ftox.2022.822993

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