Cargando…
Tentative Application of a Streamlined Protocol to Determine Organ-Specific Regulations of Deiodinase 1 and Dehalogenase Activities as Readouts of the Hypothalamus-Pituitary-Thyroid-Periphery-Axis
In animal studies, both in basic science and in toxicological assessment of potential endocrine disruptors, the state of the thyroid hormone (TH) axis is often described and defined exclusively by the concentrations of circulating THs and TSH. Although it is known that the local, organ-specific effe...
Autores principales: | Renko, Kostja, Kerp, Helena, Pape, Janina, Rijntjes, Eddy, Burgdorf, Tanja, Führer, Dagmar, Köhrle, Josef |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8978789/ https://www.ncbi.nlm.nih.gov/pubmed/35387426 http://dx.doi.org/10.3389/ftox.2022.822993 |
Ejemplares similares
-
3,5-T2—A Janus-Faced Thyroid Hormone Metabolite Exerts Both Canonical T3-Mimetic Endocrine and Intracrine Hepatic Action
por: Köhrle, Josef, et al.
Publicado: (2020) -
Restoration of type 1 iodothyronine deiodinase expression in renal cancer cells downregulates oncoproteins and affects key metabolic pathways as well as anti-oxidative system
por: Popławski, Piotr, et al.
Publicado: (2017) -
Sex-specific and inter-individual differences in biomarkers of selenium status identified by a calibrated ELISA for selenoprotein P
por: Hybsier, Sandra, et al.
Publicado: (2016) -
Comparative analysis of thyroid hormone systems in rodents with subterranean lifestyle
por: Gerhardt, Patricia, et al.
Publicado: (2023) -
New approach methods to improve human health risk assessment of thyroid hormone system disruption–a PARC project
por: Ramhøj, Louise, et al.
Publicado: (2023)