Cargando…

MDN1 Mutation Is Associated With High Tumor Mutation Burden and Unfavorable Prognosis in Breast Cancer

Background: Breast cancer (BRCA) is the most common cancer worldwide and a serious threat to human health. MDN1 mutations have been observed in several cancers. However, the associations of MDN1 mutation with tumor mutation burden (TMB) and prognosis of BRCA have not been investigated. Methods: Geno...

Descripción completa

Detalles Bibliográficos
Autores principales:	Hao, Shuai, Huang, Miao, Xu, Xiaofan, Wang, Xulin, Huo, Liqun, Wang, Lu, Gu, Jun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Genetics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8978890/ https://www.ncbi.nlm.nih.gov/pubmed/35386280 http://dx.doi.org/10.3389/fgene.2022.857836

Ejemplares similares

Association of RYR2 Mutation With Tumor Mutation Burden, Prognosis, and Antitumor Immunity in Patients With Esophageal Adenocarcinoma
por: Liu, Zaoqu, et al.
Publicado: (2021)

Significance of Tumor Mutation Burden Combined With Immune Infiltrates in the Progression and Prognosis of Advanced Gastric Cancer
por: Guo, Xiong, et al.
Publicado: (2021)

Association of a Novel Prognosis Model with Tumor Mutation Burden and Tumor-Infiltrating Immune Cells in Thyroid Carcinoma
por: Zhang, Siqin, et al.
Publicado: (2021)

The Mutation of Glu at Amino Acid 3838 of AtMDN1 Provokes Pleiotropic Developmental Phenotypes in Arabidopsis
por: Li, Peng-Cheng, et al.
Publicado: (2016)

FN1 overexpression is correlated with unfavorable prognosis and immune infiltrates in breast cancer
por: Zhang, Xiu-Xia, et al.
Publicado: (2022)

Correlations Between Tumor Mutation Burden and Immunocyte Infiltration and Their Prognostic Value in Colon Cancer
por: Zhou, Zhangjian, et al.
Publicado: (2021)

USH2A Mutation is Associated With Tumor Mutation Burden and Antitumor Immunity in Patients With Colon Adenocarcinoma
por: Sun, Yuanyuan, et al.
Publicado: (2021)

Identification and validation of a novel mitochondrion-related gene signature for diagnosis and immune infiltration in sepsis
por: Hao, Shuai, et al.
Publicado: (2023)

A machine learning-based radiomics model for prediction of tumor mutation burden in gastric cancer
por: Ma, Tingting, et al.
Publicado: (2023)

A Prognostic Model for Predicting Tumor Mutation Burden and Tumor-Infiltrating Immune Cells in Bladder Urothelial Carcinoma
por: Wang, Chengbang, et al.
Publicado: (2022)

A Joint Model Considering Measurement Errors for Optimally Identifying Tumor Mutation Burden Threshold
por: Wang, Yixuan, et al.
Publicado: (2022)

Combination of Tumor Mutational Burden and Specific Gene Mutations Stratifies Outcome to Immunotherapy Across Recurrent and Metastatic Head and Neck Squamous Cell Carcinoma
por: Peng, Ying-Peng, et al.
Publicado: (2021)

Development and Validation of a Tumor Mutation Burden-Related Immune Prognostic Signature for Ovarian Cancers
por: Cui, Mengjing, et al.
Publicado: (2022)

MYD88 mutations predict unfavorable prognosis in Chronic Lymphocytic Leukemia patients with mutated IGHV gene
por: Qin, Shu-Chao, et al.
Publicado: (2017)

PEG3 mutation is associated with elevated tumor mutation burden and poor prognosis in breast cancer
por: Zhang, Min, et al.
Publicado: (2020)

The multiple de novo copy number variant (MdnCNV) phenomenon presents with peri-zygotic DNA mutational signatures and multilocus pathogenic variation
por: Du, Haowei, et al.
Publicado: (2022)

High expression of TTC21A predicts unfavorable prognosis and immune infiltrates in clear cell renal cell carcinoma
por: Lin, Junhao, et al.
Publicado: (2022)

A Mutation-Related Long Noncoding RNA Signature of Genome Instability Predicts Immune Infiltration and Hepatocellular Carcinoma Prognosis
por: Wu, Jianhua, et al.
Publicado: (2021)

MDN brain descending neurons coordinately activate backward and inhibit forward locomotion
por: Carreira-Rosario, Arnaldo, et al.
Publicado: (2018)

Arabidopsis MDN1 Is Involved in the Establishment of a Normal Seed Proteome and Seed Germination
por: Li, Peng-Cheng, et al.
Publicado: (2019)

Characterization of tumors with ultralow tumor mutational burden in Japanese cancer patients
por: Hatakeyama, Keiichi, et al.
Publicado: (2020)

Germline PALB2 Mutations in Cancers and Its Distinction From Somatic PALB2 Mutations in Breast Cancers
por: Hu, Zhe-Yu, et al.
Publicado: (2020)

FAT3 Mutation Is Associated With Tumor Mutation Burden and Poor Prognosis in Esophageal Cancer
por: Guo, Zixin, et al.
Publicado: (2021)

MDN-0170, a New Napyradiomycin from Streptomyces sp. Strain CA-271078
por: Lacret, Rodney, et al.
Publicado: (2016)

TERT promoter mutations are frequent and show association with MED12 mutations in phyllodes tumors of the breast
por: Yoshida, Masayuki, et al.
Publicado: (2015)

Fragment Enrichment of Circulating Tumor DNA With Low-Frequency Mutations
por: Liu, Xiaojun, et al.
Publicado: (2020)

A Prognostic Model of 15 Immune-Related Gene Pairs Associated With Tumor Mutation Burden for Hepatocellular Carcinoma
por: Huo, Junyu, et al.
Publicado: (2020)

High tumor mutation burden indicates better prognosis in colorectal cancer patients with KRAS mutations
por: Wang, Jianlei, et al.
Publicado: (2022)

Association of FLG mutation with tumor mutation load and clinical outcomes in patients with gastric cancer
por: Yicheng, Fu, et al.
Publicado: (2022)

The MIDAS domain of AAA mechanoenzyme Mdn1 forms catch bonds with two different substrates
por: Mickolajczyk, Keith J, et al.
Publicado: (2022)

Significance of Tumor Mutation Burden in Immune Infiltration and Prognosis in Cutaneous Melanoma
por: Kang, Kai, et al.
Publicado: (2020)

Comprehensive analysis of genomic mutation signature and tumor mutation burden for prognosis of intrahepatic cholangiocarcinoma
por: Zhang, Rui, et al.
Publicado: (2021)

Identification of Novel Mutations in Chinese Infants With Citrullinemia
por: Cheng, Zhi, et al.
Publicado: (2022)

A new ferroptosis-related genetic mutation risk model predicts the prognosis of skin cutaneous melanoma
por: He, Jia, et al.
Publicado: (2023)

Heterogeneity within AML with CEBPA mutations; only CEBPA double mutations, but not single CEBPA mutations are associated with favourable prognosis
por: Pabst, T, et al.
Publicado: (2009)

The Effect of Ferroptosis-Related Genes on Prognosis and Tumor Mutational Burden in Hepatocellular Carcinoma
por: Zhang, Hao, et al.
Publicado: (2021)

Whole-Exome Sequencing on Circulating Tumor Cells Explores Platinum-Drug Resistance Mutations in Advanced Non-small Cell Lung Cancer
por: Chang, Yuanyuan, et al.
Publicado: (2021)

Characterization of Frequently Mutated Cancer Genes and Tumor Mutation Burden in Chinese Breast Cancer
por: Xiao, Weikai, et al.
Publicado: (2021)

An effective tool for predicting survival in breast cancer patients with de novo lung metastasis: Nomograms constructed based on SEER
por: Wang, WenYi, et al.
Publicado: (2023)

The mutation in splicing factor genes correlates with unfavorable prognosis, genomic instability, anti-tumor immunosuppression and increased immunotherapy response in pan-cancer
por: Luo, Jiangti, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_lsq9rsk39e9khstr3lrql25rra