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Perspective: Emerging strategies for determining atomic-resolution structures of macromolecular complexes within cells
In principle, electron cryo-tomography (cryo-ET) of thin portions of cells provides high-resolution images of the three-dimensional spatial arrangement of all members of the proteome. In practice, however, radiation damage creates a tension between recording images at many different tilt angles, but...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8978977/ https://www.ncbi.nlm.nih.gov/pubmed/34915129 http://dx.doi.org/10.1016/j.jsb.2021.107827 |