Cargando…
PIP5K1α is Required for Promoting Tumor Progression in Castration-Resistant Prostate Cancer
PIP5K1α has emerged as a promising drug target for the treatment of castration-resistant prostate cancer (CRPC), as it acts upstream of the PI3K/AKT signaling pathway to promote prostate cancer (PCa) growth, survival and invasion. However, little is known of the molecular actions of PIP5K1α in this...
Autores principales: | Wang, Tianyan, Sarwar, Martuza, Whitchurch, Jonathan B, Collins, Hilary M, Green, Tami, Semenas, Julius, Ali, Amjad, Roberts, Christopher J, Morris, Ryan D, Hubert, Madlen, Chen, Sa, El-Schich, Zahra, Wingren, Anette G, Grundström, Thomas, Lundmark, Richard, Mongan, Nigel P, Gunhaga, Lena, Heery, David M, Persson, Jenny L |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8979106/ https://www.ncbi.nlm.nih.gov/pubmed/35386201 http://dx.doi.org/10.3389/fcell.2022.798590 |
Ejemplares similares
-
FcγRIIIa receptor interacts with androgen receptor and PIP5K1α to promote growth and metastasis of prostate cancer
por: Larsson, Per Flodbring, et al.
Publicado: (2022) -
Targeted suppression of AR-V7 using PIP5K1α inhibitor overcomes enzalutamide resistance in prostate cancer cells
por: Sarwar, Martuza, et al.
Publicado: (2016) -
Targeted inhibition of ERα signaling and PIP5K1α/Akt pathways in castration‐resistant prostate cancer
por: Semenas, Julius, et al.
Publicado: (2020) -
Establishment of Prostate Tumor Growth and Metastasis Is Supported by Bone Marrow Cells and Is Mediated by PIP5K1α Lipid Kinase
por: Karlsson, Richard, et al.
Publicado: (2020) -
The functional interlink between AR and MMP9/VEGF signaling axis is mediated through PIP5K1α/pAKT in prostate cancer
por: Larsson, Per, et al.
Publicado: (2019)