Hyperpolarised NMR to aid molecular profiling of electronic cigarette aerosols

Signal amplification by reversible exchange (SABRE) hyperpolarisation is used to enhance the NMR signals of nicotine and acrolein in methanol-d(4) solutions of electronic cigarette aerosols. Consequently, detection of 74 μM nicotine is possible in just a single scan (1)H NMR spectrum. The first exam...

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Detalles Bibliográficos
Autores principales: Tickner, Ben. J., Komulainen, Sanna, Palosaari, Sanna, Heikkinen, Janne, Lehenkari, Petri, Zhivonitko, Vladimir V., Telkki, Ville-Veikko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2022
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8979170/
https://www.ncbi.nlm.nih.gov/pubmed/35425197
http://dx.doi.org/10.1039/d1ra07376a
Descripción
Sumario:Signal amplification by reversible exchange (SABRE) hyperpolarisation is used to enhance the NMR signals of nicotine and acrolein in methanol-d(4) solutions of electronic cigarette aerosols. Consequently, detection of 74 μM nicotine is possible in just a single scan (1)H NMR spectrum. The first example of an aldehyde hyperpolarised using SABRE is demonstrated and we work towards novel real-world applications of SABRE-hyperpolarised NMR for chemical analysis.

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