Hyperpolarised NMR to aid molecular profiling of electronic cigarette aerosols

Signal amplification by reversible exchange (SABRE) hyperpolarisation is used to enhance the NMR signals of nicotine and acrolein in methanol-d(4) solutions of electronic cigarette aerosols. Consequently, detection of 74 μM nicotine is possible in just a single scan (1)H NMR spectrum. The first exam...

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Autores principales: Tickner, Ben. J., Komulainen, Sanna, Palosaari, Sanna, Heikkinen, Janne, Lehenkari, Petri, Zhivonitko, Vladimir V., Telkki, Ville-Veikko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2022
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8979170/
https://www.ncbi.nlm.nih.gov/pubmed/35425197
http://dx.doi.org/10.1039/d1ra07376a
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author Tickner, Ben. J.
Komulainen, Sanna
Palosaari, Sanna
Heikkinen, Janne
Lehenkari, Petri
Zhivonitko, Vladimir V.
Telkki, Ville-Veikko
author_facet Tickner, Ben. J.
Komulainen, Sanna
Palosaari, Sanna
Heikkinen, Janne
Lehenkari, Petri
Zhivonitko, Vladimir V.
Telkki, Ville-Veikko
author_sort Tickner, Ben. J.
collection PubMed
description Signal amplification by reversible exchange (SABRE) hyperpolarisation is used to enhance the NMR signals of nicotine and acrolein in methanol-d(4) solutions of electronic cigarette aerosols. Consequently, detection of 74 μM nicotine is possible in just a single scan (1)H NMR spectrum. The first example of an aldehyde hyperpolarised using SABRE is demonstrated and we work towards novel real-world applications of SABRE-hyperpolarised NMR for chemical analysis.
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spelling pubmed-89791702022-04-13 Hyperpolarised NMR to aid molecular profiling of electronic cigarette aerosols Tickner, Ben. J. Komulainen, Sanna Palosaari, Sanna Heikkinen, Janne Lehenkari, Petri Zhivonitko, Vladimir V. Telkki, Ville-Veikko RSC Adv Chemistry Signal amplification by reversible exchange (SABRE) hyperpolarisation is used to enhance the NMR signals of nicotine and acrolein in methanol-d(4) solutions of electronic cigarette aerosols. Consequently, detection of 74 μM nicotine is possible in just a single scan (1)H NMR spectrum. The first example of an aldehyde hyperpolarised using SABRE is demonstrated and we work towards novel real-world applications of SABRE-hyperpolarised NMR for chemical analysis. The Royal Society of Chemistry 2022-01-10 /pmc/articles/PMC8979170/ /pubmed/35425197 http://dx.doi.org/10.1039/d1ra07376a Text en This journal is © The Royal Society of Chemistry https://creativecommons.org/licenses/by/3.0/
spellingShingle Chemistry
Tickner, Ben. J.
Komulainen, Sanna
Palosaari, Sanna
Heikkinen, Janne
Lehenkari, Petri
Zhivonitko, Vladimir V.
Telkki, Ville-Veikko
Hyperpolarised NMR to aid molecular profiling of electronic cigarette aerosols
title Hyperpolarised NMR to aid molecular profiling of electronic cigarette aerosols
title_full Hyperpolarised NMR to aid molecular profiling of electronic cigarette aerosols
title_fullStr Hyperpolarised NMR to aid molecular profiling of electronic cigarette aerosols
title_full_unstemmed Hyperpolarised NMR to aid molecular profiling of electronic cigarette aerosols
title_short Hyperpolarised NMR to aid molecular profiling of electronic cigarette aerosols
title_sort hyperpolarised nmr to aid molecular profiling of electronic cigarette aerosols
topic Chemistry
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8979170/
https://www.ncbi.nlm.nih.gov/pubmed/35425197
http://dx.doi.org/10.1039/d1ra07376a
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