Transplantation of human iPSC-derived muscle stem cells in the diaphragm of Duchenne muscular dystrophy model mice

Duchenne muscular dystrophy (DMD) is an intractable genetic muscular disorder characterized by the loss of DYSTROPHIN. The restoration of DYSTROPHIN is expected to be a curative therapy for DMD. Because muscle stem cells (MuSCs) can regenerate damaged myofibers with full-length DYSTROPHIN in vivo, t...

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Detalles Bibliográficos
Autores principales: Miura, Yasutomo, Sato, Mase, Kuwahara, Toshie, Ebata, Tomoki, Tabata, Yasuhiko, Sakurai, Hidetoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8979463/
https://www.ncbi.nlm.nih.gov/pubmed/35377913
http://dx.doi.org/10.1371/journal.pone.0266391

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