The Probe for Renal Organic Cation Secretion (4-Dimethylaminostyryl)-N-Methylpyridinium (ASP+)) Shows Amplified Fluorescence by Binding to Albumin and Is Accumulated In Vivo

Accumulation of uremic toxins may lead to the life-threatening condition “uremic syndrome” in patients with advanced chronic kidney disease (CKD) requiring renal replacement therapy. Clinical evaluation of proximal tubular secretion of organic cations (OC), of which some are uremic toxins, is desire...

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Detalles Bibliográficos
Autores principales: Engbjerg, Jacob Schade, Costanzo, Vincenzo, Sardella, Donato, Bordoni, Luca, Jakobsen, Steen, D'Apolito, Luciano, Frøkiær, Jørgen, Trepiccione, Francesco, Capasso, Giovambattista, Frische, Sebastian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8979605/
https://www.ncbi.nlm.nih.gov/pubmed/35418808
http://dx.doi.org/10.1155/2022/7908357

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