Cargando…

Effect of Early Swimming on the Behavior and Striatal Transcriptome of the Shank3 Knockout Rat Model of Autism

BACKGROUND: Autism spectrum disorder (ASD) is a developmental disorder characterized by social behavior deficits and stereotyped behaviors in childhood that lacks satisfactory medical intervention. Early swimming intervention is a noninvasive method combining enriched environment and exercise, which...

Descripción completa

Detalles Bibliográficos
Autores principales:	Meng, Yunchen, Xu, Dan, Zhang, Weinan, Meng, Wenshu, Lan, Xingyu, Wang, Xiaoxi, Li, Mingjuan, Zhang, Xiaoyan, Zhao, Yu, Yang, Haodong, Zhang, Rong, Zhen, Zhiping
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove 2022
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8979754/ https://www.ncbi.nlm.nih.gov/pubmed/35387206 http://dx.doi.org/10.2147/NDT.S357338

Ejemplares similares

Swimming exercise is a promising early intervention for autism‐like behavior in Shank3 deletion rats
por: Xu, Dan, et al.
Publicado: (2022)

Changes in the urinary proteome in rats with regular swimming exercise
por: Meng, Wenshu, et al.
Publicado: (2021)

Striatal Transcriptome and Interactome Analysis of Shank3-overexpressing Mice Reveals the Connectivity between Shank3 and mTORC1 Signaling
por: Lee, Yeunkum, et al.
Publicado: (2017)

Identification of a novel Shank2 transcriptional variant in Shank2 knockout mouse model of autism spectrum disorder
por: Lee, Yong-Seok, et al.
Publicado: (2020)

Environmental enrichment has minimal effects on behavior in the Shank3 complete knockout model of autism spectrum disorder
por: Hulbert, Samuel W., et al.
Publicado: (2018)

Brain region-specific disruption of Shank3 in mice reveals a dissociation for cortical and striatal circuits in autism-related behaviors
por: Bey, Alexandra L., et al.
Publicado: (2018)

Hyperactivity and Hypermotivation Associated With Increased Striatal mGluR1 Signaling in a Shank2 Rat Model of Autism
por: Modi, Meera E., et al.
Publicado: (2018)

An autism-linked missense mutation in SHANK3 reveals the modularity of Shank3 function
por: Wang, Li, et al.
Publicado: (2019)

Shank3 mutant mice display autistic-like behaviours and striatal dysfunction
por: Peça, João, et al.
Publicado: (2011)

Influence of maternal zinc supplementation on the development of autism-associated behavioural and synaptic deficits in offspring Shank3-knockout mice
por: Vyas, Yukti, et al.
Publicado: (2020)

Dietary Zinc Supplementation Prevents Autism Related Behaviors and Striatal Synaptic Dysfunction in Shank3 Exon 13–16 Mutant Mice
por: Fourie, Chantelle, et al.
Publicado: (2018)

Altered mGluR5-Homer scaffolds and corticostriatal connectivity in a Shank3 complete knockout model of autism
por: Wang, Xiaoming, et al.
Publicado: (2016)

Increased ribosomal protein levels and protein synthesis in the striatal synaptosome of Shank3-overexpressing transgenic mice
por: Jin, Chunmei, et al.
Publicado: (2021)

Restoring Shank3 in the rostral brainstem of shank3ab−/− zebrafish autism models rescues sensory deficits
por: Kozol, Robert A., et al.
Publicado: (2021)

Transcriptional and functional complexity of Shank3 provides a molecular framework to understand the phenotypic heterogeneity of SHANK3 causing autism and Shank3 mutant mice
por: Wang, Xiaoming, et al.
Publicado: (2014)

Abnormal Striatal Development Underlies the Early Onset of Behavioral Deficits in Shank3B(−/−) Mice
por: Peixoto, Rui Tiago, et al.
Publicado: (2019)

Association between physical health and physical activity behaviors for children aged 3–6 years in kindergarten: A cross-sectional study from China
por: Xiong, Xin, et al.
Publicado: (2022)

Association study of SHANK3 gene polymorphisms with autism in Chinese Han population
por: Qin, Jian, et al.
Publicado: (2009)

Intestinal dysmotility in a zebrafish (Danio rerio) shank3a;shank3b mutant model of autism
por: James, David M., et al.
Publicado: (2019)

Expression profiles of the autism-related SHANK proteins in the human brain
por: Woelfle, Sarah, et al.
Publicado: (2023)

Shank2/3 double knockout-based screening of cortical subregions links the retrosplenial area to the loss of social memory in autism spectrum disorders
por: Garrido, Débora, et al.
Publicado: (2022)

Novel Therapeutic Approach for Autism Spectrum Disorder: Focus on SHANK3
por: Uchino, Shigeo, et al.
Publicado: (2015)

A recurrent SHANK3 frameshift variant in Autism Spectrum Disorder
por: Loureiro, Livia O., et al.
Publicado: (2021)

Neuromotor Development in the Shank3 Mouse Model of Autism Spectrum Disorder
por: Pillerová, Miriam, et al.
Publicado: (2022)

Autism-associated gene shank3 is necessary for social contagion in zebrafish
por: Kareklas, Kyriacos, et al.
Publicado: (2023)

SHANK2 mutations associated with Autism Spectrum Disorder cause hyperconnectivity of human neurons
por: Zaslavsky, Kirill, et al.
Publicado: (2019)

Role of the Autism Risk Gene Shank3 in the Development of Atherosclerosis: Insights from Big Data and Mechanistic Analyses
por: Chang, Hsiu-Wen, et al.
Publicado: (2023)

Lack of Association between NLGN3, NLGN4, SHANK2 and SHANK3 Gene Variants and Autism Spectrum Disorder in a Chinese Population
por: Liu, Yanyan, et al.
Publicado: (2013)

Transcriptome analysis of Shank3-overexpressing mice reveals unique molecular changes in the hypothalamus
por: Jin, Chunmei, et al.
Publicado: (2018)

Single-molecule fluorescence in-situ hybridization reveals that human SHANK3 mRNA expression varies during development and in autism-associated SHANK3 heterozygosity
por: Taylor, Samuel E., et al.
Publicado: (2018)

Activation of the medial preoptic area (MPOA) ameliorates loss of maternal behavior in a Shank2 mouse model for autism
por: Grabrucker, Stefanie, et al.
Publicado: (2021)

Evidence that modifier loci have no effect on phenotypic severity in SHANK3-linked autism
Publicado: (2014)

Targeting Shank3 deficiency and paresthesia in autism spectrum disorder: A brief review
por: Huang, Min, et al.
Publicado: (2023)

Tau reduction attenuates autism-like features in Fmr1 knockout mice
por: Zhao, Shanshan, et al.
Publicado: (2023)

William Frederick Shanks
Publicado: (1926)

Shank3 Transgenic and Prenatal Zinc-Deficient Autism Mouse Models Show Convergent and Individual Alterations of Brain Structures in MRI
por: Schoen, Michael, et al.
Publicado: (2019)

Combined Transcriptome and Metabolome Analysis of Smooth Muscle of Myostatin Knockout Cattle
por: Gu, Mingjuan, et al.
Publicado: (2023)

Meta-analysis of SHANK Mutations in Autism Spectrum Disorders: A Gradient of Severity in Cognitive Impairments
por: Leblond, Claire S., et al.
Publicado: (2014)

Dysfunctional cerebellar Purkinje cells contribute to autism-like behaviour in Shank2-deficient mice
por: Peter, Saša, et al.
Publicado: (2016)

Downregulation of the Autism Spectrum Disorder Gene Shank2 Decreases Bone Mass in Male Mice
por: Ahmad, Mubashir, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_1tsdob3fo22esdolf5gk42782s